Sickle Cell Anemia is caused by mutations in the gene that make hemoglobin (protein beta-globin). It is an iron-rich compound and this makes the blood red. Hemoglobin helps red blood cells transport oxygen from the lungs to other parts of the body. When you have sickle cell anemia, the abnormal hemoglobin makes the red blood cells hard, sticky and deformed. Sickle cell genes are inherited from generation to generation.
In cases where sickle genes are present in both parents, their children may have the following situations -
25% of children do not have the possibility of disease.
50% of children are born with hidden genetic factors but no external symptoms are seen.
25% of children are born with sickle cell.
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