There are many reasons for hypopititarism. In many cases, the cause of hypopituitarism is a tumor in the pituitary gland. As the pituitary tumor grows in size, it suppresses and damages the pituitary tissue. The tumor can also narrow the optic nerves, causing visual disturbances. However, some other diseases and conditions can also cause damage to the pituitary glands leading to problems such as hypopituitarism, such as: head trauma Brain surgery Head or neck radiation treatment Decreased blood flow to the brain or pituitary gland (stroke) or bleeding to the brain or pituitary gland Some medicines can also cause this such as narcotics, high dose corticosteroids or some cancer drugs called checkpoint inhibitors. Pituitary gland inflammation due to abnormal immune system Brain infections, such as meningitis, or infections that can spread to the brain Infiltrative diseases that affect many parts of the body, including sarcoidosis.
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